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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| B6.129S1-Is(14)2Rdf/J (Cat. No.: CEMM-07250360) | Inquiry | |
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These 14qC3-MDR mice carry a floxed region that encompases a region corresponding to a minimal deleted region involved in most common B cell chronic lymphocytic leukemias in humans. They have applications in studies related to tumorigenesis and therapeutic management of chronic lymphocytic leukemia.
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| B6.129S1-Is(14C3)3Rdf/J (Cat. No.: CEMM-07250361) | Inquiry | |
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These 14qC3-CDRfl mice carry a floxed segment that encompasses sequence corresponding to a common deleted region (CDR) involved in most common B cell chronic lymphocytic leukemias in humans. They have applications in studies related to tumorigenesis and therapeutic management of chronic lymphocytic leukemia.
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| B6(Cg)-Sh2d3ctm1Ebp/J (Cat. No.: CEMM-07250363) | Inquiry | |
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These Shep1flox mutant mice possess loxP sites on either side of exon 7 of the Sh2d3c (SH2 domain containing 3C) gene and have applications in studies related to cell adhesion and migration.
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| B6.129-Anapc2tm1Hez/J (Cat. No.: CEMM-07250364) | Inquiry | |
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These mice possess loxP sites flanking exons 2 of the anaphase promoting complex subunit 2 (Anapc2) gene and may have applications in studies related to cell cycle regulation and early embryonic development.
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| 129S-Slc11a2tm2Nca/J (Cat. No.: CEMM-07250366) | Inquiry | |
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These Dmt1fl mice possess loxP sites flanking exons 6-8 of the solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (Slc11a2) gene and have applications in studies related to anemia, iron homeostasis and micronutrient and drug absorption in the intestine.
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| STOCK Glstm2.1Sray/J (Cat. No.: CEMM-07250371) | Inquiry | |
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These mice possess loxP sites flanking exon 1 of the glutaminase (Gls) gene and have applications in studies of cellular energy metabolism.
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| B6(Cg)-Grin1tm1c(EUCOMM)Wtsi/ZwzJ (Cat. No.: CEMM-07250408) | Inquiry | |
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These Grin12lox mice possess loxP sites flanking exon 6 of the glutamate receptor, ionotropic, NMDA1 (zeta 1), Grin1, gene and have applications in studies related to the involvement of NMDA receptors in synaptogenesis, synaptic plasticity and neurological disorders.
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| B6;129-Llgl1tm1Vv/J (Cat. No.: CEMM-07250425) | Inquiry | |
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These floxed mutant mice possess loxP sites flanking exon 2 of the Llgl1 gene. This strain may be useful for generating conditional mutations in applications related to the study of cell polarity.
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| 129-Atmtm2.1Fwa/J (Cat. No.: CEMM-07250449) | Inquiry | |
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These mice possess loxP sites flanking exons 57 and 58 of the ataxia telangiectasia mutated homolog (human), Atm, gene and have applications in studies related to Ataxia-Telangiectasia, DNA double-strand-break repair, and DNA double-strand-break joining processes.
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| B6(129S4)-Cacna1gtm1Stl/J (Cat. No.: CEMM-07250466) | Inquiry | |
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These mice possess loxP sites flanking exons 9 through 12 of the calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna1g) gene and have applications in studies related to circadian rhythm and sleep patterns.
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For Research Use Only.