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STOCK Glstm2.1Sray/J
Cat. No.: CEMM-07250371
Common Name: floxGLS1; GLS1lox
These mice possess loxP sites flanking exon 1 of the glutaminase (Gls) gene and have applications in studies of cellular energy metabolism.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Glstm2.1Sray
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Gls
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| Gene Name |
glutaminase
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
129S1/Sv-Oca2+ Tyr+ Kitl+
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| Molecular Note |
The targeting vector was designed to insert a loxP site 16 bp before the start codon in exon 1 and a loxP-flanked neomycin cassette in intron 1. Cre-mediated recombination removed the floxed neo cassette leaving exon 1 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF1/J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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