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129S-Slc11a2tm2Nca/J
Cat. No.: CEMM-07250366
These Dmt1fl mice possess loxP sites flanking exons 6-8 of the solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (Slc11a2) gene and have applications in studies related to anemia, iron homeostasis and micronutrient and drug absorption in the intestine.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Slc11a2tm2Nca
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Slc11a2
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| Gene Name |
solute carrier family 11 (proton-coupled divalent metal ion transporters)
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| Chromosome |
15
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| MGI Accession ID | show more close |
| Strain of Origin |
129S4/SvJae
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| Molecular Note |
A single loxP site was inserted into intron 5 and a loxP flanked cytidine deaminase (CD)- neomycin cassette was inserted into intron 8. Transient Cre expression removed the CD-neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
129S1/SvImJ 129S4/SvJaeJ
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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