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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| C57BL/6J-Tg(Neurod1-cre/ERT2)M1Fcal/J (Cat. No.: CEMM-07250580) | Inquiry | |
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These mice express Cre-ERT2 under the direction of the murine Neurod1 promoter making them useful for spatial- and temporal-specific recombination in Neurod1-expressing cells during development or adulthood.
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| B6.129(SJL)-Kcnk3tm1.2Daba/J (Cat. No.: CEMM-07250582) | Inquiry | |
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Kcnk3f/f floxed mice may be useful for studying pH sensitivity and chemosensitivity in respiratory neurons.
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| B6.129(SJL)-Kcnk9tm1.2Daba/J (Cat. No.: CEMM-07250589) | Inquiry | |
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Kcnk9f/f floxed mice may be useful for studying pH sensitivity and chemosensitivity in respiratory neurons.
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| B6.Cg-Foxp2tm1.1Sfis/CfreJ (Cat. No.: CEMM-07250592) | Inquiry | |
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The Foxp2floxΔneo allele has loxP sites flanking the DNA-binding motif (exons 12-14) of the forkhead box P2 gene. The mice allow Cre recombinase-inducible Foxp2 knockout, and may be useful for studying speech and language development during embryogenesis/neurogenesis, speech impairment, dyslexia, cognitive function/flexibility, sensorimotor integration and motor-skill learning.
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| STOCK Lmnatm1.1Yxz/J (Cat. No.: CEMM-07250595) | Inquiry | |
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Lmnaflox/flox mice possess loxP sites flanking exon 2 of the lamin A gene, making them useful for studying the role of Lamin-A in specific cell types, and its influence on the progression of human diseases.
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| B6;129S-Wnt5atm1.1Krvl/J (Cat. No.: CEMM-07250601) | Inquiry | |
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Wnt5afl/fl floxed mice may be useful for studying the branching and extension of sympathetic axons in the peripheral nervous system.
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| C57BL/6-Nrxn2tm4Sud/J (Cat. No.: CEMM-07250603) | Inquiry | |
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Nrxn2flox mice may be useful for generating tissue specific deletions of neurexin II in neuronal cells.
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| B6;129S6-Adgrl3tm1Sud/J (Cat. No.: CEMM-07250604) | Inquiry | |
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These Lphn3flox mice may be useful for generating tissue specific deletions of Adgrl3 in neuronal cells.
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| B6(Cg)-Syde1tm1c(EUCOMM)Hmgu/ScheiJ (Cat. No.: CEMM-07250607) | Inquiry | |
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mSYD1Aflox mice may be useful for studying synaptogenic signaling and vesicle docking.
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| STOCK Chn1tm1.1Schei/J (Cat. No.: CEMM-07250608) | Inquiry | |
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Chn1flox mice may be useful for studying cortical and spinal motor circuits.
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