B6.129(SJL)-Kcnk9tm1.2Daba/J

Cat. No.: CEMM-07250589

Kcnk9f/f floxed mice may be useful for studying pH sensitivity and chemosensitivity in respiratory neurons.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Kcnk9tm1.2Daba
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Allele Name
targeted mutation 1.2
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Kcnk9
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Gene Name
potassium channel
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Chromosome
15
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MGI Accession ID show more close
Site of Expression
Kcnk9 is expressed in cerebellar granule cells, locus coeruleus, motor neurons, pontine nuclei, some cells in the neocortex, habenula, olfactory bulb granule cells, and cells in the external plexiform layer of the olfactory bulb.
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Strain of Origin
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Molecular Note
A targeting vector was designed to insert a FRT flanked neomycin resistance (neo) cassette followed by a loxP site upstream of exon 2, and a second loxP site downstream of exon 2. Flpe mediatedrecombination removed the FRT flanked neo cassette leaving exon 2 floxed.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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