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B6.129(SJL)-Kcnk3tm1.2Daba/J
Cat. No.: CEMM-07250582
Kcnk3f/f floxed mice may be useful for studying pH sensitivity and chemosensitivity in respiratory neurons.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Kcnk3tm1.2Daba
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| Allele Name |
targeted mutation 1.2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Kcnk3
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| Gene Name |
potassium channel
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| Chromosome |
5
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| MGI Accession ID | show more close |
| Site of Expression |
Kcnk3 is expressed in cerebellar granule cells, locus coeruleus, motor neurons, pontine nuclei, some cells in the neocortex, habenula, olfactory bulb granule cells, and cells in the external plexiform layer of the olfactory bulb
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| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A targeting vector was designed to insert a FRT flanked neomycin resistance (neo) cassette followed by a loxP site upstream of exon 2, and a second loxP site downstream of exon 2. Flp mediated recombination removed the FRT flanked neo cassette leaving exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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