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B6.Cg-Foxp2tm1.1Sfis/CfreJ
Cat. No.: CEMM-07250592
Common Name: Foxp2floxΔneo
The Foxp2floxΔneo allele has loxP sites flanking the DNA-binding motif (exons 12-14) of the forkhead box P2 gene. The mice allow Cre recombinase-inducible Foxp2 knockout, and may be useful for studying speech and language development during embryogenesis/neurogenesis, speech impairment, dyslexia, cognitive function/flexibility, sensorimotor integration and motor-skill learning.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Foxp2tm1.1Sfis
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Foxp2
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| Gene Name |
forkhead box P2
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
B6.Cg-Thy1a
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| Molecular Note |
Flp-mediated recombination was used to remove the FLPe-neo cassette between exons 11 and 12 leaving a floxed exon 12 through 14 region.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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