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FVB/NJ-Grid1em1Mpan/J
Cat. No.: CEMM-07251066
Common Name: floxed Grid1
Grid1 floxed mice carry a CRISPR/Cas9 generated mutation resulting in loxP sites surrounding exon 4 of the (Grid1) gene. This strain may be useful for studying heightened aggression found in a subset of autism spectrum disorder (ASD) cases.
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Status | Live Mouse Frozen Embryo |
Age | 4 weeks 12 weeks Customized Age |
Sex | Male Female |
GENETICS | |
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Allele Symbol |
Grid1em1Mpan
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Allele Name |
endonuclease-mediated mutation 1
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Allele Attributes |
Conditional ready (e.g. floxed)
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Gene Symbol |
Grid1
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Gene Name |
glutamate receptor
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Chromosome |
14
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MGI Accession ID | show more close |
Strain of Origin |
FVB/NJ
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Molecular Note |
CRISPER/Cas9 genome editing used signal guide RNAs (TCCAGCCCCAGGATATAAGG and CGGTTCCTTCACAGACCACG) to introduce loxP sites to surround exon 4.
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HUSBANDRY | |
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Suggested Controls |
FVB/NJ
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Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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