FVB/NJ-Grid1em1Mpan/J

Cat. No.: CEMM-07251066

Common Name: floxed Grid1
Grid1 floxed mice carry a CRISPR/Cas9 generated mutation resulting in loxP sites surrounding exon 4 of the (Grid1) gene. This strain may be useful for studying heightened aggression found in a subset of autism spectrum disorder (ASD) cases.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Grid1em1Mpan
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Allele Name
endonuclease-mediated mutation 1
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Allele Attributes
Conditional ready (e.g. floxed)
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Gene Symbol
Grid1
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Gene Name
glutamate receptor
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Chromosome
14
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MGI Accession ID show more close
Strain of Origin
FVB/NJ
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Molecular Note
CRISPER/Cas9 genome editing used signal guide RNAs (TCCAGCCCCAGGATATAAGG and CGGTTCCTTCACAGACCACG) to introduce loxP sites to surround exon 4.
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HUSBANDRY
Suggested Controls
FVB/NJ
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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