B6.129S-Scpep1tm1Jomm/J

Cat. No.: CEMM-07250233

Common Name: Scpep1 lacZ KO
In these mice endogenous gene function of the serine carboxypeptidase 1 (Scpep1) gene is replaced with a β-galactosidase (lacZ) gene. These mice may be useful for studying vascular remodeling after injury and vascular occlusive diseases.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Scpep1tm1Jomm
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Allele Name
targeted mutation 1
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Allele Attributes
Null/Knockout
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Gene Symbol
Scpep1
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Gene Name
serine carboxypeptidase 1
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Chromosome
11
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Strain of Origin
129S/SvEv
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Molecular Note
A targeting vector was designed to replace exons 1-2 of the serine carboxypeptidase 1 (Scpep1) gene with a beta-galactosidase (lacZ) gene and a loxP-flanked neomycin resistance cassette.
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HUSBANDRY
Suggested Controls
C57BL/6J Wild-type from the colony
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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