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STOCK Wwtr1tm1Hmc Yap1tm1Hmc/WranJ
Cat. No.: CEMM-07250807
Common Name: Taz flox/Yap flox
These double floxed mutant mice possess loxP sites flanking exon 2 of both the Wwtr1 and Yap1 genes. This strain may be useful for generating conditional mutations in applications related to the Hippo signaling pathway, organogenesis, tumorigenesis, and tumor suppression.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Wwtr1tm1Hmc
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Wwtr1
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| Gene Name |
WW domain containing transcription regulator 1
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| Chromosome |
3
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A loxP site was inserted in intron 1 and a loxP site and FRT flanked neo cassette were inserted in intron 2 via homologous recombination.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as double homozygotes.
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For Research Use Only.
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