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FVB/N-Tg(Mpz-cre)26Mes/J
Cat. No.: CEMM-07250383
Common Name: mP0TOTA(Cre); mPoTOTA-Cre; MPZ(Cre); Tg98.1; Tg(Mpz-cre)1Mfel
These transgenic mice contain the myelin protein zero (P0) (Mpz) promoter driving expression of Cre recombinase in Schwann cell. These mice may be useful for studying the myelination of peripheral nerve cells.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Mpz-cre)26Mes
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| Allele Name |
transgene insertion 26
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Mpz-cre)26Mes
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| Gene Name |
transgene insertion 26
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| Chromosome |
15
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase is expressed in Schwann cells, but not in sensory neurons.
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| Strain of Origin |
FVB/NTac
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| Molecular Note |
This transgene expresses Cre recombinase under the control of a mouse Mpz promoter. This transgene is expressed in Schwann cells, but not in sensory neurons. Multiple copies of the transgene construct were integrated into the 35-45 cM position on Chromosome 15.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
FVB/NJ
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| Breeding Considerations |
When maintaining a live colony, hemizygous mice may be bred to wildtype (non-carrier) mice from the colony or to FVB/NJ inbred mice.
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For Research Use Only.
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