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C57BL/6J-Grm3tm1.1Conn/J
Cat. No.: CEMM-07251129
Common Name: Grm3Fl
Grm3Fl floxed mice have loxP sites flanking exon 3 of the Grm3 gene. These mice may be useful when studying the role of mGlu3 receptors in the regulation of synaptic plasticity and cognition.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Grm3tm1.1Conn
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Grm3
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| Gene Name |
glutamate receptor
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| Chromosome |
5
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
The targeting construct is designed to insert a loxP site upstream of exon 3 and a FRT flanked neomycin resistance cassette, followed by a second loxP site, inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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