Online Inquiry
B6.129S6-Apoetm1.1Mae/MazzJ
Cat. No.: CEMM-07250670
Common Name: ApoE-Flox
These floxed mutant mice possess loxP sites flanking exon 3 of the Apoe gene. This strain may be useful for generating conditional mutations in applications related to the regulation of lipoprotein and cholesterol metabolism, neurovascular function, inflammation and in the pathophysiology of neurodegenerative cardiovascular diseases.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Apoetm1.1Mae
show more
close
|
| Allele Name |
targeted mutation 1.1
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
show more
close
|
| Gene Symbol |
Apoe
show more
close
|
| Gene Name |
apolipoprotein E
show more
close
|
| Chromosome |
7
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
show more
close
|
| Molecular Note |
The targeting vector contains a loxP site and an FRT flanked neo cassette inserted downstream of exon 3 of the targeted gene, and another loxP site inserted upstream of exon 3. Flp-mediated recombination removed the FRT flanked neo cassette leaving exon 3 floxed.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
show more
close
|
| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
show more
close
|
For Research Use Only.
Related Products