Online Inquiry
C57BL/6-Marckstm2.1Pjb/J
Cat. No.: CEMM-07250987
Common Name: MARCKSF
MARCKSF mutant mice possess loxP sites flanking exon 2 of the Marcks (myristoylated alanine rich protein kinase C substrate) gene and may be useful in generating conditional mutations to study the regulation of cell permeability and secretion.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Marckstm2.1Pjb
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Marcks
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| Gene Name |
myristoylated alanine rich protein kinase C substrate
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| Chromosome |
10
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6
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| Molecular Note |
A loxP site was inserted upstream of exon 2. A floxed neomycin resistance cassette was inserted downstream of exon 2. Cre-mediated recombination removed the selection cassette and left exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
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| Breeding Considerations |
When maintaining a live colony, these mice are bred by homozygote sibling matings.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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