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B6(SJL)-Gabra2tm2.1Uru/J
Cat. No.: CEMM-07251097
Common Name: α2fl
The α2fl mice have loxP sites flanking exon 5 of the Gabra2 gene. These mice may be useful for studying physiologic and therapeutic properties of GABAA α-subunits in such diseases as epilepsy or substance abuse disorders.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gabra2tm2.1Uru
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Gabra2
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| Gene Name |
gamma-aminobutyric acid (GABA) A receptor
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| Chromosome |
5
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6N
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| Molecular Note |
A loxP site was inserted upstream of exon 5. An FRT flanked neo cassette with a 5' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neo cassette and left exon 5 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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