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STOCK Drd1tm2.1Stl/J
Cat. No.: CEMM-07250573
These floxed mutant mice possess loxP sites flanking the single exon of the Ddr1a gene. This strain may be useful for generating conditional mutations for applications related to behavioral responses.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Drd1tm2.1Stl
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Drd1
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| Gene Name |
dopamine receptor D1
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| Chromosome |
13
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| MGI Accession ID | show more close |
| Strain of Origin |
B6.Cg-Thy1a
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| Molecular Note |
A loxP site was introduced 5' of the targeted gene's single exon and an FRT loxP-(neo-tk)-FRT loxP (LFNT) cassette was introduced 3'. Cre-mediated recombination excised the neo cassette, leaving the coding region flanked by loxP sites.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
Heterozygous and homozygous floxed mice are viable and fertile.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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