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B6N.Cg-Tg(Camk2a-cre)T29-1Stl/J
Cat. No.: CEMM-07250412
These CaMKIIalpha-cre T29-1 transgenic mice have the mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a) promoter driving Cre recombinase expression in the forebrain, specifically to the CA1 pyramidal cell layer in the hippocampus.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Camk2a-cre)T29-1Stl
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| Allele Name |
transgene insertion T29-1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Camk2a-cre)T29-1Stl
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| Gene Name |
transgene insertion T29-1
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Forebrain; pyramidal cell layer.
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| Strain of Origin |
(C57BL x BALB/c)F1
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| Molecular Note |
This transgene directs the expression of Cre recombinase under the control of the alpha subunit of the calcium/calmodulin-dependent protein kinase II promoter. Cre recombinase activity was detected in the CA1 region of the hippocampus.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
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| Breeding Considerations |
Mice were bred to C57BL/6NJ inbred mice for many generations using a marker-assisted, speed congenic approach to generate this C57BL/6NJ-congenic strain. When maintaining the live congenic colony, hemizygous mice may be bred with wildtype (non-carrier) mice from the colony or with C57BL/6NJ inbred mice. For Cre-lox experiments and to avoid germline deletion/global recombination of floxed alleles, researchers may consider breeding Tg(Camk2a-cre)T29-1Stl females with floxed males.
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For Research Use Only.
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