Online Inquiry
B6N.129S1(Cg)-Lrrc7tm1.2Mabk/J
Cat. No.: CEMM-07250401
Densinflox mice possess loxP sites flanking exon 3, a region encoding the transcriptional start site of the leucine rich repeat containing 7 (Lrrc7) gene, and may be useful in studying behavioral and synaptic defects associated with schizophrenia and autism spectrum disorder.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Lrrc7tm1.2Mabk
show more
close
|
| Allele Name |
targeted mutation 1.2
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
show more
close
|
| Gene Symbol |
Lrrc7
show more
close
|
| Gene Name |
leucine rich repeat containing 7
show more
close
|
| Chromosome |
3
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
129S1/Sv-Oca2+ Tyr+ Kitl+
show more
close
|
| Molecular Note |
A targeting vector was designed to insert a single loxP site upstream of exon 3, and a loxP-flankedhygromycin resistance (hygro) cassette downstream of exon 3. Cre-mediated recombination removed the hygro cassette and left exon 3 floxed.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
show more
close
|
| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
show more
close
|
For Research Use Only.
Related Products