FVB.129(B6)-Slc44a2tm1.1Tec/J

Cat. No.: CEMM-07250689

Common Name: Slc44a2flox
These floxed mutant mice possess loxP sites flanking exons 3 through 10 of the Slc44a2 gene, also known as Ctl2. This strain may be useful for generating conditional mutations in applications related to cochlear hair cell survival and antibody-induced hearing loss.
Inquiry
Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Slc44a2tm1.1Tec
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed)
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Gene Symbol
Slc44a2
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Gene Name
solute carrier family 44
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Chromosome
9
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MGI Accession ID show more close
Strain of Origin
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Molecular Note
A targeting vector containing an FRT flanked PGK-Neo selection cassette followed by a loxP site inserted upstream of exon 3 and another loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the FRT flanked neo cassette leaving exons 3 through 10 floxed.
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HUSBANDRY
Suggested Controls
FVB/NJ
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Breeding Considerations
When maintaining a live colony, these mice can be bred as homozygotes.
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Breeding Strategy
Homozygote x Homozygote
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For Research Use Only.
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