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B6.Cg-Sntb1tm1.1Scf/J
Cat. No.: CEMM-07251023
Common Name: Sntb1flox
Sntb1flox mice have loxP sites flanking exon 1 of the Sntb1 gene. These mice may be useful when studying the dystrophin complex and Duchenne muscular dystrophy.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Sntb1tm1.1Scf
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Sntb1
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| Gene Name |
syntrophin
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| Chromosome |
15
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| MGI Accession ID | show more close |
| Strain of Origin |
(C3H x C57BL/6)F1
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| Molecular Note |
A loxP site was inserted upstream of exon 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 1. Subsequent flp-mediated recombination removed the neo cassette, leaving a conditional-ready allele with exon 1 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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