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STOCK Cckarem1(cre)Shah/J

Cat. No.: CEMM-07251083

Common Name: CckarCre
CckarCre CRISPR-derived knock-in mice are designed to have 2A-Cre sequence inserted into the 3' UTR of the cholecystokinin A receptor (Cckar) gene. The endogenous Cckar promoter/enhancer regions direct expression of Cre recombinase to parts of the reproductive system, the central and peripheral nervous systems, and the gut, without disrupting endogenous gene expression. These mice are useful for studying mating behaviors, food intake, pancreatic exocrine secretion, gall bladder contractility and GI motility.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Cckarem1(cre)Shah
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Allele Name
endonuclease-mediated mutation 1
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Allele Attributes
Recombinase-expressing
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Gene Symbol
Cckar
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Gene Name
cholecystokinin A receptor
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Chromosome
5
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MGI Accession ID
6885886
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Strain of Origin
C57BL/6J
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Molecular Note
Using CRISPR/Cas9-mediated homologous recombination, the 2A-Cre was inserted into the 3'UTR in exon 5 of the Cckar gene.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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