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B6.Cg-Slco2a1em1(cre)Ngai/TasicJ
Cat. No.: CEMM-07251105
Common Name: Slco2a1-P2A-Cre
Slco2a1-P2A-Cre knock-in mice are designed to have Cre recombinase expression/activity directed by the endogenous solute carrier organic anion transporter family member 2a1 promoter/enhancer sequences. These mice may be used to generate conditional mutations for studying function of Slco2a1-expressing cells.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Slco2a1em1(cre)Ngai
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Recombinase-expressing; Epitope tag
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| Gene Symbol |
Slco2a1
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| Gene Name |
solute carrier organic anion transporter family
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| Chromosome |
9
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S4/SvJae)F1
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| Molecular Note |
Using CRISPR/Cas9 technology, a P2A-Cre and a Myc-tag were inserted after the STOP codon of the solute carrier organic anion transporter family member 2a1 gene (Slco2a1).
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony or to C57BL/6J inbred mice. it has not been attempted to make this strain homozygous.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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