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B6.Cg-Tg(Camk2a-cre)2Szi/J
Cat. No.: CEMM-07250634
Common Name: R1ag#5
These R1Ag5 mice express nuclear-localized Cre recombinase from the mouse Camk2a promoter in the adult brain, with high levels in all forebrain structures, and moderate levels in the cerebellum as well as testis.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Camk2a-cre)2Szi
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| Allele Name |
transgene insertion 2
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Camk2a-cre)2Szi
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| Gene Name |
transgene insertion 2
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase is expressed in the forebrain (mainly in the cortex and striatum).
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| Strain of Origin |
(CBA x C57BL/6J)F1
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| Molecular Note |
This transgene expresses Cre recombinase under the control of the mouse calcium/calmodulin-dependent protein kinase II (Camk2a) promoter. Expression of Cre recombinase from this transgene was detected in high levels in the forebrain, moderate levels in the cerebellum and is active by E18.5 in the embryonic cortex.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Noncarrier
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| Breeding Considerations |
Hemizygotes are viable and fertile. For Cre-lox experiments and to avoid/minimize germline deletion of the floxed allele, researchers may consider breeding R1ag#5 females to floxed males. See Detailed Description for more details.
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For Research Use Only.
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