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B6.Cg-Igf2bp2tm1.1Thor/J
Cat. No.: CEMM-07250920
Common Name: Imp2 floxed
These floxed mutant mice possess loxP sites flanking exons 4 and 5 of the Igf2bp2 gene. This strain may be useful for generating conditional mutations in applications related to the developing brain, neural stem cells, as well as metabolism and diabetes.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Igf2bp2tm1.1Thor
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Igf2bp2
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| Gene Name |
insulin-like growth factor 2 mRNA binding protein 2
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| Chromosome |
16
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| MGI Accession ID | show more close |
| Strain of Origin |
Not Specified
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| Molecular Note |
The targeting vector contains an FRT flanked neomycin selection cassette and a loxP site inserted downstream of exon 5 of the targeted gene, and another loxP site was inserted upstream of exon 4. Flp-mediated recombination removed the FRT flanked neo cassette leaving exons 4 through 5 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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