Online Inquiry
B6;CBA-Tg(Sox10-cre)1Wdr/J
Cat. No.: CEMM-07250576
Sox10-Cre mice express Cre recombinase in the entire post-migratory post-otic neural crest population during early embryonic development.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Sox10-cre)1Wdr
show more
close
|
| Allele Name |
transgene insertion 1
show more
close
|
| Allele Attributes |
Recombinase-expressing
show more
close
|
| Gene Symbol |
Tg(Sox10-cre)1Wdr
show more
close
|
| Gene Name |
transgene insertion 1
show more
close
|
| Chromosome |
UN
show more
close
|
| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
show more
close
|
| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase is expressed in the entire post-migratory post-otic neural crest population during early embryonic development.
show more
close
|
| Strain of Origin |
(C57BL/6 x CBA)F1
show more
close
|
| Molecular Note |
A nuclear targete Cre recombinase sequence replaced the entire coding region of Sox10 in a P1-derived artificial chromosome (PAC ID RP21-529-I6). Several founders were obtained. A representative line was designated line 1.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6CBAF1/J
show more
close
|
| Breeding Considerations |
When maintaining a live colony hemizygous mice may be bred to wildtype (non-carrier) mice from the colony or to C57BL/6J. Of note, CD BioScience live colony exhibits white belly spots (not linked to presence of the transgene). For Cre-lox experiments and to avoid/minimize germline deletion of the floxed allele, researchers may consider breeding Sox10-Cre females to floxed males.
show more
close
|
| Breeding Strategy |
Noncarrier x Hemizygote; Hemizygote x Noncarrier
show more
close
|
For Research Use Only.
Related Products