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B6;CBA-Tg(Cyp19a1-cre)1Dlc/J
Cat. No.: CEMM-07250890
Common Name: Cyp19a1-Cre
Cyp19a1-Cre BAC transgenic mice express cre recombinase from the mouse Cyp19a1 (aromatase) promoter, faithfully recapitulating brain expression patterns of the endogenous mouse gene.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Cyp19a1-cre)1Dlc
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Cyp19a1-cre)1Dlc
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre is expressed in the medial amygdala and other sites across the brain.
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| Strain of Origin |
C57BL/6 x CBA
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| Molecular Note |
A Cre coding sequence was inserted in front of the start codon of the mouse Cyp19a1 gene. Additionally, the ATG codon of the Cyp19a1 gene in the BAC was additionally mutated into a TTG stop codon.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Noncarrier
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| Breeding Considerations |
Homozygotes and hemizygotes are viable and fertile.
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| Breeding Strategy |
Noncarrier x Hemizygote; Hemizygote x Noncarrier
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For Research Use Only.
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