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C57BL/6J-Akt3em1Shzb/Mmjax
Cat. No.: CEMM-07250961
Akt3fl conditional knock-out mice have loxP sites flanking exon 3 of the thymoma viral proto-oncogene 3 gene. These mice may be useful for studying the role of AKT3 signaling in inflammatory demyelinating disease.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Akt3em1Shzb
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Akt3
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| Gene Name |
thymoma viral proto-oncogene 3
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
CRISPR/Cas9 endonuclease-mediated genome editing was used to insert a loxP site in intron 2 (GAGCCCATCTTCAGTCTGAC) and a second loxP site in intron 3 (CTTGCATGTTTAACTAGGGCTGG) of the gene.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice are bred by homozygote sibling matings.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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