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STOCK Gt(ROSA)26Sortm1Phep/J
Cat. No.: CEMM-07250599
These Rosa26SNAPCaaX reporter mice conditionally express membrane-localized SNAP-tag from the Gt(ROSA)26Sor promoter upon cre-mediated excision of a floxed stop cassette. Cells expressing the SNAP-tag can be selectively labeled through treatment with benzylguanine (BG)-linked compounds, including synthetic fluorophores.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm1Phep
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; No functional change
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| Gene Symbol |
Gt(ROSA)26Sor
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| Gene Name |
gene trap ROSA 26
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| Chromosome |
6
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| Expressed Genes |
SNAP-tag
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129P2/OlaHsd)F1
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| Molecular Note |
A targeting construct introduced the following components, in order, to intron 1 of the Gt(ROSA)26Sor gene: CAG-FRT loxP-stop-loxP-(SNAP-tag/CaaX)-WPRE-pA-AttB-Pr-FRT Neo-pA-AttP. The SNAP-Tag construct contains a membrane associated CaaX consensus sequence.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Homozygous and heterozygous mice are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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