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B6.129S6(SJL)-Prkcztm1.1Rlh/J
Cat. No.: CEMM-07250539
The catalytic domain of the mouse Prkcz gene is flanked by loxP sites in this conditional mutant strain. It enables the creation of Cre-mediated PKM-ζ isoform knockouts, useful in studies of synaptic plasticity, learning and memory.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Prkcztm1.1Rlh
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Prkcz
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| Gene Name |
protein kinase C
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| Chromosome |
4
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
Exon 11 was floxed. Flp-mediated recombination removed an FRT flanked neo cassette inserted downstream of exon 11.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Homozygous and heterozygous floxed mice are viable and fertile.
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For Research Use Only.
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