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B6;129S4-Btg2tm1(cre/ERT2)Zjh/J
Cat. No.: CEMM-07251054
Common Name: Tis21-2A-CreER
Tis21-2A-CreER knock-in mice express tamoxifen-inducible CreERT2 fusion protein from the mouse Btg2 (BTG anti-proliferation factor 2; also called Tis21) promoter in BTG2-positive cortical glutamatergic pyramidal neurons (PyNs).
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Btg2tm1(cre/ERT2)Zjh
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Btg2
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| Gene Name |
B cell translocation gene 2
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S4/SvJae)F1
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| Molecular Note |
The allele was generated by inserting a 2A-CreER expression cassette in-frame before the STOP codon of the Btg2 gene. The targeting vectors generated using BAC clones from the RPCI-23&24 library were electroporated into a 129SVj/B6 hybrid ES cell line (v6.5). The Resulting ES cell clones were used for tetraploid complementation to obtain male heterozygous mice.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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