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B6.129S1(Cg)-Gdnftm1.1Neas/J
Cat. No.: CEMM-07250285
These Gdnfflox mutant mice possess loxP sites flanking exon 3 of the glial cell line derived neurotrophic factor (Gdnf) gene. This strain may be useful for studying gamma motor neuron function in motor control.
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Status | Live Mouse Frozen Embryo |
Age | 4 weeks 12 weeks Customized Age |
Sex | Male Female |
GENETICS | |
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Allele Symbol |
Gdnftm1.1Neas
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Allele Name |
targeted mutation 1.1
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Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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Gene Symbol |
Gdnf
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Gene Name |
glial cell line derived neurotrophic factor
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Chromosome |
15
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MGI Accession ID | show more close |
Strain of Origin |
129S1/Sv-Oca2+ Tyr+ Kitl+
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Molecular Note |
An FRT flanked neo cassette was inserted upstream of a modified exon 3 in which the coding sequence was floxed. Flp mediated recombination removed the neo cassette leaving the coding sequence floxed.
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HUSBANDRY | |
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Suggested Controls |
C57BL/6J
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Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred.
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For Research Use Only.
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