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B6.129S1(Cg)-Eomestm1.1Bflu/J
Cat. No.: CEMM-07250333
Common Name: Eomes fl
These floxed mutant mice possess loxP sites flanking exon 2 of the eomesodermin homolog (Eomes) gene. This strain may be useful for studying T cell-mediated immune response, immune surveillance and editing, and embryonic development.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Eomestm1.1Bflu
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Eomes
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| Gene Name |
eomesodermin
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| Chromosome |
9
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| MGI Accession ID | show more close |
| Strain of Origin |
129S1/Sv-Oca2+ Tyr+ Kitl+
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| Molecular Note |
The second exon was floxed and a FRT flanked neo cassette inserted within intron 2 by homologous recombination. The selection cassette was removed by Flp mediated recombination.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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