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B6;129S-Gt(ROSA)26Sortm1(Cdkn1c)Jfpa/J
Cat. No.: CEMM-07250475
Common Name: R26loxpTA-p57k
R26loxpTA-p57 mice allow Cre recombinase-inducible expression of the cell cycle inhibitor p57Kip2 (Cdkn1c), resulting in cell cycle arrest in G1 phase of the cre expressing cells.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm1(Cdkn1c)Jfpa
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Inserted expressed sequence
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| Gene Symbol |
Gt(ROSA)26Sor
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| Gene Name |
gene trap ROSA 26
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| Chromosome |
6
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| Expressed Genes |
Cdkn1c, cyclin-dependent kinase inhibitor 1C (P57), mouse, laboratory
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| MGI Accession ID | show more close |
| Strain of Origin |
129S7/SvEvBrd-Hprtb-m2
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| Molecular Note |
A 1.4 kb cDNA containing the complete open reading frame of the mouse gene was placed under the control of a loxP-flanked transcriptional termination sequence. This construct was inserted between exons 1 and 2.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony, or to C57BL/6J inbred mice. The donating investigator reports that homozygous mice (R26loxpTA-p57k/k) have the same phenotype as heterozygous mice.
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For Research Use Only.
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