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STOCK Bhlhe40tm1Rhli/NgcTesDamJ
Cat. No.: CEMM-07250986
Common Name: Bhlhe40 cko; Bhlhb2 cko
The Bhlhe40 conditional knockout (cko) strain may be useful in applications related to circadian rhythms, cellular growth, immune responses, and transcriptional regulation.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Bhlhe40tm1Rhli
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Bhlhe40
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| Gene Name |
basic helix-loop-helix family
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
129S1/Sv-Oca2+ Tyr+ Kitl+
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| Molecular Note |
An FRT flanked neo cassette with a 5' loxP site was inserted downstream of exon 4 and an additional loxP site was inserted upstream of exon 1. Germ-line flp-mediate recombination was used to remove the neo cassette leaving exons 1 through 4 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Heterozygotes and homozygotes are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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