B6;129-Vangl1tm1.1Nat/J

Cat. No.: CEMM-07250422

The third (and largest) coding exon of Vangl1 (vang-like 1 (van gogh, Drosophila)) is flanked by loxP sites in this conditional knockout allele.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Vangl1tm1.1Nat
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Vangl1
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Gene Name
VANGL planar cell polarity 1
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Chromosome
3
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MGI Accession ID show more close
Strain of Origin
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Molecular Note
A loxP site was inserted at an SpeI site 384 bp 3' of the third coding exon, in intron 3. A second loxP together with a Frt-PGK-neo-Frt selection cassette site was inserted at a StuI site 279 bp 5' of the exon, in intron 2. Flp-mediated recombination removed the neo cassette and left exon 3 floxed.
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HUSBANDRY
Breeding Considerations
Heterozygotes and homozygotes are viable and fertile.
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For Research Use Only.
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