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B6.129S6(Cg)-Resttm1.1Jhsi/J
Cat. No.: CEMM-07250543
Common Name: REST/NRSFloxP
These floxed mutant mice possess loxP sites flanking exon 4 of the Rest gene. This strain may be useful for generating conditional mutations in applications related to the study of neurogenesis.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Resttm1.1Jhsi
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Rest
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| Gene Name |
RE1-silencing transcription factor
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| Chromosome |
5
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
A loxP site was inserted upstream of exon 4. An FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exon 4 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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For Research Use Only.
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