B6;129-Oprd1tm1.1Cgrf/KffJ

Cat. No.: CEMM-07250774

Common Name: Oprd1fl
Oprd1fl/fl mice possess loxP sites flanking exon 2 of the opioid receptor, delta 1 (Oprd1) gene. These mice may be useful in studying mood disorders and chronic pain.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Oprd1tm1.1Cgrf
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Oprd1
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Gene Name
opioid receptor
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Chromosome
4
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MGI Accession ID show more close
Strain of Origin
129
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Molecular Note
A floxed hygromycin resistance gene was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the selection cassette and left exon 2 floxed.
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HUSBANDRY
Suggested Controls
B6129SF2/J
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy
Homozygote x Homozygote
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For Research Use Only.
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