B6.Cg-Dpp6tm1.2Dahn/J

Cat. No.: CEMM-07250756

Common Name: Dpp6fl
These conditional knockout mice possess loxP sites flanking exon 2 of dipeptidylpeptidase 6 (Dpp6), a gene involved in the regulation of potassium channels. This strain may be useful in studies of dendritic function and potassium currents.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Dpp6tm1.2Dahn
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Allele Name
targeted mutation 1.2
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Dpp6
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Gene Name
dipeptidylpeptidase 6
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Chromosome
5
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Strain of Origin
B6.Cg-Thy1a
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Molecular Note
A loxP site was inserted upstream of exon 2. An FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. FLP-mediated recombination removed the neo cassette.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
While maintaining a live colony, these mice are bred as homozygotes.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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