Online Inquiry
B6;129-Ntstm1(cre)Mgmj/J
Cat. No.: CEMM-07250352
Common Name: NtsCre
These mutant mice feature a nondisruptive Cre recombinase knock-in at the endogenous Neurotensin locus. They may be useful for generating conditional mutations in studies related to metabolism and energy homeostasis.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ntstm1(cre)Mgmj
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Nts
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| Gene Name |
neurotensin
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| Chromosome |
10
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase activity is detected in neurotensin expressing neurons.
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| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
An IRES-Cre sequence was inserted into the 3' UTR of the Nts gene between the stop codon and the polyadenylation sequence. A floxed neo cassette was inserted downstream of the transcribed Nts sequence.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF1/J
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| Breeding Considerations |
The Donating Investigator reports that when maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Homozygote x Homozygote
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| Coat Color |
Due to the mixed B6 and 129 background, mice from this strain may be Agouti, Black or Albino
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For Research Use Only.
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