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B6;129-Shhtm2Amc/J
Cat. No.: CEMM-07250013
Common Name: Shhc
These floxed mutant mice possess loxP sites flanking exon 2 of the Shh gene. This strain may be useful for generating conditional mutations in applications related to in studies of developmental defects resulting from disruption of Shh-dependent pathways.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Shhtm2Amc
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Shh
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| Gene Name |
sonic hedgehog
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| Chromosome |
5
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
LoxP sites were inserted into intronic sequences flanking exon 2. This mutation has no effect on the normal function of this gene.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
129X1/SvJ B6129SF2/J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together. Coat color expected from breeding is Agouti.
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For Research Use Only.
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