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B6;129-Dlg3tm1Rlh/J
Cat. No.: CEMM-07250262
When crossed with a Cre recombinase-expressing strain, this floxed Dlg3 (discs, large homolog 3 (Drosophila); SAP102) strain is useful in eliminating tissue-specific expression of the gene. Defective expression of this gene is associated with deficits in synaptic plasticity and deterioration of learning/memory functions.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Dlg3tm1Rlh
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Dlg3
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| Gene Name |
discs large MAGUK scaffold protein 3
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| Chromosome |
X
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A genomic region including six exons encoding the PDZ1 and PDZ2 regions of the targeted gene were flanked by loxP sites.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintained as a live colony, homozygotes or heterozygotes/hemizygotes may be bred.
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For Research Use Only.
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