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B6.129(Cg)-Itm2btm1Ldad/J
Cat. No.: CEMM-07250390
Common Name: BRI2f
These BRI2f/f mice possess loxP sites flanking exon 2 of the Itm2b gene and may have applications in studies related to dementia and Alzheimer's Disease.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Itm2btm1Ldad
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Itm2b
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| Gene Name |
integral membrane protein 2B
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| Chromosome |
14
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| MGI Accession ID | show more close |
| Strain of Origin |
129
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| Molecular Note |
A loxP site was inserted 200 bp 5' of exon 2 and a floxed PGK-neo cassette was inserted in intron 2 via homologous recombination. The floxed PGK-neo cassette was deleted via in vivo Cre-mediated recombination, leaving exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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