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STOCK Tg(mI56i-cre, EGFP)1Kc/J
Cat. No.: CEMM-07250514
These Dlx5/6-Cre-IRES-EGFP transgenic mice may be useful for generating specific deletions of floxed alleles in ventral forebrain neuronal populations with fluorescent expression.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(mI56i-cre,EGFP)1Kc
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(mI56i-cre,EGFP)1Kc
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
GFP, Green Fluorescent Protein; Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase and EGFP fluorescence are expressed in differentiating and migrating ventral forebrain neurons, including GABAergic neurons.
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| Strain of Origin |
FVB/N
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| Molecular Note |
The transgene was designed with a 0.5 kb fragment containing the id6/id5 enhancer and a beta-globin minimal enhancer placed immediately upstream of a Cre recombinase coding sequence and an internal ribosomal entry site (IRES)-enhanced green fluorescent fusion protein. The bicistronic construct expresses in the SVC and forming mantle. Three lines were Created.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Noncarrier
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| Breeding Considerations |
When maintaining a live colony, hemizygotes may be bred to non-carrier (wildtype) siblings or C57BL/6J inbred mice.
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For Research Use Only.
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