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STOCK Tg(Gsx1-cre)6Wql/J
Cat. No.: CEMM-07250735
Common Name: Gsx1cre
These Gsx1cre transgenic mice express Cre recombinase under the control of the Gsx1 promoter and may be useful for generating conditional mutations for studying gain/loss of function or fate mapping in Gsx1 expressing neurons.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Gsx1-cre)6Wql
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| Allele Name |
transgene insertion 6
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Gsx1-cre)6Wql
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| Gene Name |
transgene insertion 6
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase is expressed primarily in the dorsal spinal cord and hindbrain beginning around E13.5. Cre recombinase activity is also detected in Gsx1-expressing cells in the spinal cord ventral horn and dorsal root ganglia.
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| Strain of Origin |
C57BL/6
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| Molecular Note |
The mouse bacterial artificial chromosome (BAC) BX1725 (RP24-352K2) containing the entire Gsx1 gene, was modified by fusing a Cre recombinase coding sequence into the first encoding exon of the Gsx1 gene. The resulting transgenic mice from founder line 6 were crossed to Create the line.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Noncarrier
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| Breeding Considerations |
When maintaining a live colony, hemizygous mice may be bred together, to wildtype siblings, or to C57BL/6J inbred mice. The Donating Investigator has not attempted to make this strain homozygous.
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For Research Use Only.
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