STOCK Tg(Eno2-cre/ERT2)1Pohlk/J

Cat. No.: CEMM-07250479

Nse-CreERT2 transgenic mice express the tamoxifen inducible cre/ERT2 fusion gene in cerebellar lobular granule cells and in a few hippocampal dentate gyrus granule cells as directed by the rat Eno2 (enolase 2, gamma, neuronal) promoter. Cre-ERT2 fusion gene activity is inducible by the administration of tamoxifen.

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Status	Live Mouse Frozen Embryo
Age	4 weeks 12 weeks Customized Age
Sex	Male Female

GENETICS
Allele Symbol	Tg(Eno2-cre/ERT2)1Pohlk show more close
Allele Name	transgene insertion 1 show more close
Allele Attributes	Recombinase-expressing; Inducible show more close
Gene Symbol	Tg(Eno2-cre/ERT2)1Pohlk show more close
Gene Name	transgene insertion 1 show more close
Chromosome	UN show more close
Expressed Genes	cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene show more close
MGI Accession ID	5510668 show more close
Site of Expression	These transgenic mice express the Tamoxifen inducible cre/ERT2 fusion gene in cerebellar lobular granule cells and in a few hippocampal dentate gyrus granule cells. show more close
Strain of Origin	FVB/N show more close
Molecular Note	A transgenic construct containing the Cre/ERT2 (Cre recombinase and estrogen receptor 1 tamoxifen binding domain fusion gene) under the control of the rat Eno2 (enolase 2, gamma, neuronal) promoter, was injected into fertilized FVB/N mouse eggs. Founder line 1 was subsequently established. The mice were crossed to mice on a mixed background, containing C57BL/6, 129, and ICR. show more close

HUSBANDRY
Suggested Controls	C57BL/6J show more close
Breeding Considerations	When maintaining a live colony, hemizygous mice may be bred together, to wildtype siblings, or to C57BL/6J inbred mice. The Donating Investigator has not attempted to make the strain homozygous. show more close

For Research Use Only.