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STOCK Slc32a1tm1Lowl/J
Cat. No.: CEMM-07250247
Common Name: Vgatflox
These floxed Slc32a1tm1Lowl (also commonly referred to as Vgatflox/flox) mice possess loxP sites flanking exon 2 of the Slc32a1 (or Vgat) gene. These mice may be useful for studying the physiological effect of GABAergic neurotransmission on the regulation of energy balance.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Slc32a1tm1Lowl
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Slc32a1
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| Gene Name |
solute carrier family 32 (GABA vesicular transporter)
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| Chromosome |
2
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
LoxP sites were inserted flanking exon 2 and an FRT flanked kan/neo cassette was inserted via homologous recombination. The kan/neo cassette was subsequently removed via in vivo Flp mediated recombination.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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