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B6.129-Grm5tm1.1Jixu/J
Cat. No.: CEMM-07250686
Common Name: mGluR5loxP
Exon 7 of the mouse Grm5 gene is flanked by loxP sites. Cre-mediated excision of the exon results in a knockout allele.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Grm5tm1.1Jixu
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Grm5
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| Gene Name |
glutamate receptor
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| Chromosome |
7
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A floxed neo cassette was inserted into intron 7, 720 bp downstream of exon 7, and a third loxP site was inserted upstream of exon 7 via homologous recombination. The neo cassette was then removed via Cre mediated recombination.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
Homozygous and heterozygous floxed mice are viable and fertile.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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