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STOCK Tenm3tm1(cre)Luo/J
Cat. No.: CEMM-07250886
Common Name: Ten3cre
Ten3cre knock-in/knock-out mice express cre recombinase from the mouse Tenm3 (teneurin transmembrane protein 3) promoter.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tenm3tm1(cre)Luo
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Recombinase-expressing; Null/Knockout
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| Gene Symbol |
Tenm3
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| Gene Name |
teneurin transmembrane protein 3
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| Chromosome |
8
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre expression mimics the pattern of the wildtype gene (Tenm3) that is expressed in areas of the hippocampal region.
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| Strain of Origin |
(C57BL/6 x 129S6/SvEvTac)F1
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| Molecular Note |
Cre recombinase, a synthetic intron, woodchuck hepatitis virus post-transcriptional regulatory element (WPRE), bovine growth hormone polyA (bGH pA) and an FRT flanked PGK-neomycin cassette replace sequences of the mouse Tenm3 gene immediately 3' of the ATG transcriptional start site in exon 1 via homologous recombination in embryonic stem cells. The neomycin cassette was retained.The mutation functions as a Tenm3 null allele lacking protein expression.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Homozygotes are often smaller than heterozygotes, but both homozygotes and heterozygotes are viable and fertile.
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| Breeding Strategy |
Wild-type x Heterozygote; Heterozygote x Wild-type
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For Research Use Only.
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