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STOCK Tcerg1ltm1.1(cre/ERT2)Zjh/J
Cat. No.: CEMM-07250969
Common Name: Tcerg1l-2A-CreER
Tcerg1l-2A-CreER knock-in mice express tamoxifen-inducible CreERT2 fusion protein from the mouse Tcerg1l (transcription elongation regulator 1-like) promoter in TCERG1L-positive neurons of the neocortex, hypothalamus and tectum.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tcerg1ltm1.1(cre/ERT2)Zjh
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Tcerg1l
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| Gene Name |
transcription elongation regulator 1-like
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| Chromosome |
7
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S4/SvJae)F1
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| Molecular Note |
A targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a CreER fusion gene followed by a FRT flanked neo cassette upstream of the stop codon of the Tcerg1l (transcription elongation regulator 1-like) gene. CreER incorporates Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand-binding domain. The neomycin cassette was excised with Flp recombinase.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
Heterozygous and homozygous mice are viable and fertile.
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For Research Use Only.
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