Online Inquiry
B6N.129S-Kat5tm1.1Ge/J
Cat. No.: CEMM-07251005
Common Name: TIP60flox
TIP60 floxed mice have loxP sites flanking exons 1-9 of the K(lysine) acetyltransferase 5 (Kat5) gene. Exposure to Cre recombinase removes the floxed sequence - creating a null allele. These TIP60 floxed mice may be useful in the study of circadian rhythms and related diseases.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Kat5tm1.1Ge
show more
close
|
| Allele Name |
targeted mutation 1.1
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed)
show more
close
|
| Gene Symbol |
Kat5
show more
close
|
| Gene Name |
K(lysine) acetyltransferase 5
show more
close
|
| Chromosome |
19
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
129S/SvEv
show more
close
|
| Molecular Note |
Exons 1-9 were flanked by loxP sites and an FRT flanked neomycin selection cassette. The neomycin selection cassette was removed via FLP-mediated recombination in the germline.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
show more
close
|
| Breeding Considerations |
Both heterozygous and homozygous mice are viable and fertile with normal breeding, and no reported gross phenotypic or behavioral abnormalities. When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony or to C57BL/6J inbred mice. Alternatively, homozygous mice may be bred together.
show more
close
|
| Breeding Strategy |
Heterozygote x Heterozygote
show more
close
|
For Research Use Only.
Related Products